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Neonatal Senning Operation: A Single-Center Experience
Stacey Chen, MD, Sujata B. Chakravarti, MD, James C. Nielsen, MD, Puneet Bhatla, MD, Shivanand S. Medar, Gillian L. Henry, MD, Ralph S. Mosca, MD, T.K. Susheel Kumar, MD.
NYU Langone Health, New York, NY, USA.
Objective(s): The arterial switch operation continues to be the standard of care for dextro-transposition of the great arteries (d-TGA). However, certain conditions may preclude an arterial switch operation. We report our center’s experience with the Senning operation in neonates.
Methods: This is a single-center retrospective review of neonates with d-TGA who underwent the Senning operation from May 2022 to January 2024.
Results: During the study period, 4 male patients with an average weight of 4.28±1.12kg underwent the modified Senning operation. Median age at operation was 25 days (range 15-100 days). Pre-operative transthoracic echocardiogram demonstrated moderate-to-severe pulmonary valve stenosis with subpulmonary obstruction in all patients. Three patients (75%) had complex coronary anatomy and 3 patients (75%) had a small muscular ventricular septal defect. A gore-tex patch was used to construct the floor of the systemic venous pathway and in-situ pericardium was used to construct the pulmonary venous pathway. The average cross-clamp time was 98.25±9.43 minutes. The average cardiopulmonary bypass time was 179.5±39.37 minutes. Median length of stay was 27 days (range 24-29 days) and median time to follow-up was 114 days (range 65-594 days). Survival was 100%. There were no incidences of atrial arrhythmias, diaphragmatic paralysis, or systemic and/or pulmonary venous baffle obstruction or leak. Right ventricular and tricuspid valve function was preserved in all patients.
Conclusions: The Senning operation is a good option in certain subgroups of patients with d-TGA unsuitable for the standard arterial switch operation. It can be performed safely in neonates with excellent outcomes.
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